ARV-825

Catalog No.: A16859
BRD4 Inhibitor
ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology.
Grouped product items
Product Name Price Stock Qty
ARV-825 5mg
$160.00
In stock
ARV-825 10mg
$260.00
In stock
ARV-825 50mg
$760.00
In stock
ARV-825 100mg
$1,260.00
In stock
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Biological Activity
Discription ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology.
Product Information
Catalog Num A16859
Formula C46H47ClN8O9S
Molecular Weight 923.44
CAS Number 1818885-28-7
SMILES O=C(NC1=CC=C(OCCOCCOCCOCCNC2=CC=CC(C(N3C(CC4)C(NC4=O)=O)=O)=C2C3=O)C=C1)C[C@H]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5
Synonyms ARV825, ARV 825
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 97 mg/mL (105.04 mM)
Water Insoluble
Ethanol 3 mg/mL (3.24 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.83 mL 54.15 mL 108.29 mL
0.5 mM 2.17 mL 10.83 mL 21.66 mL
1 mM 1.08 mL 5.41 mL 10.83 mL
5 mM 0.22 mL 1.08 mL 2.17 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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