ARV-825

Name: ARV-825
SKU: A16859
Price: 128 USD
Rating: 5 (288 reviews)

Catalog No.: A16859

BRD4 Inhibitor

ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology.

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Grouped product items
Product Name	Price	Stock
ARV-825 5mg	Special Price $128.00 Regular Price $160.00	In stock
ARV-825 10mg	Special Price $208.00 Regular Price $260.00	In stock
ARV-825 50mg	Special Price $608.00 Regular Price $760.00	In stock
ARV-825 100mg	Special Price $1,008.00 Regular Price $1,260.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription	ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology.

Product Information

Catalog Num	A16859
Formula	C46H47ClN8O9S
Molecular Weight	923.44
CAS Number	1818885-28-7
SMILES	O=C(NC1=CC=C(OCCOCCOCCOCCNC2=CC=CC(C(N3C(CC4)C(NC4=O)=O)=O)=C2C3=O)C=C1)C[C@H]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5
Synonyms	ARV825, ARV 825
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	97 mg/mL (105.04 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (3.24 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.83 mL	54.15 mL	108.29 mL
0.5 mM	2.17 mL	10.83 mL	21.66 mL
1 mM	1.08 mL	5.41 mL	10.83 mL
5 mM	0.22 mL	1.08 mL	2.17 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂