ARV-825

Catalog No.: A16859

BRD4 Inhibitor

ARV-825

ARV-825 Chemical Structure

CAS NO. 1818885-28-7

ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology.

Availability: In stock

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5 mg

Regular Price: $160.00

Special Price $128.00

10 mg

Regular Price: $260.00

Special Price $208.00

50 mg

Regular Price: $760.00

Special Price $608.00

100 mg

Regular Price: $1,260.00

Special Price $1,008.00

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Biological Activity

ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology.
In vitro DMSO 97 mg/mL (105.04 mM)
Water Insoluble
Ethanol 3 mg/mL (3.24 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.83 mL 54.15 mL 108.29 mL
0.5 mM 2.17 mL 10.83 mL 21.66 mL
1 mM 1.08 mL 5.41 mL 10.83 mL
5 mM 0.22 mL 1.08 mL 2.17 mL

*The above data is based on the productmolecular weight 923.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16859
Actions Inhibitor
CAS No. 1818885-28-7
Formula C46H47ClN8O9S
M. Wt 923.44
Purity >98%
Synonyms ARV825, ARV 825
SMILES O=C(NC1=CC=C(OCCOCCOCCOCCNC2=CC=CC(C(N3C(CC4)C(NC4=O)=O)=O)=C2C3=O)C=C1)C[[email protected]]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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