Catalog No.: A21581

PKCθ selective inhibitor


AS2521780 Chemical Structure

CAS NO. 1214726-89-2

AS2521780 is a novel PKCθ selective inhibitor with an IC50 of 0.48 nM.

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Biological Activity

AS2521780 is a novel PKCθ selective inhibitor with an IC50 of 0.48 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.26 mL 91.28 mL 182.56 mL
0.5 mM 3.65 mL 18.26 mL 36.51 mL
1 mM 1.83 mL 9.13 mL 18.26 mL
5 mM 0.37 mL 1.83 mL 3.65 mL

*The above data is based on the productmolecular weight 547.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21581
Actions Inhibitor
CAS No. 1214726-89-2
Formula C30H41N7OS
M. Wt 547.76
Purity >98%
Synonyms AS 2521780, AS-2521780
SMILES CSC1=C(CNC2=NC=C(C#N)C(NC[[email protected]@]3(C[[email protected]@H](C4)C5NC[[email protected]]6CC[[email protected]](O)CC6)C[[email protected]]4C[[email protected]]5C3)=N2)C=CC=N1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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