Catalog No.: A12592
calcineurin inhibitor
Ascomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.
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Ascomycin 10mg
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Ascomycin 25mg
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Ascomycin 10mM * 1mL in DMSO
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Biological Activity
Discription Ascomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.
Target Value
Product Information
Catalog Num A12592
Formula C43H69NO12
Molecular Weight 792.01
CAS Number 104987-12-4
SMILES CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\C
Synonyms FK 520, FR 900520, FK520, FR900520

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 98 mg/mL (123.73 mM)
Water Insoluble
Ethanol 98 mg/mL (123.73 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.63 mL 63.13 mL 126.26 mL
0.5 mM 2.53 mL 12.63 mL 25.25 mL
1 mM 1.26 mL 6.31 mL 12.63 mL
5 mM 0.25 mL 1.26 mL 2.53 mL
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