Ascomycin

Catalog No.: A12592

calcineurin inhibitor

Ascomycin Chemical Structure

CAS NO. 104987-12-4

Ascomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.

Availability: In stock

Package Price Qty
10 mg
$25.00
25 mg
$40.00
10mM * 1mL in DMSO
$415.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Ascomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases.
Targets
calcineurin phosphatase
49 nM
In vitro DMSO 100 mg/mL (126.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (126.26 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.63 mL 63.13 mL 126.26 mL
0.5 mM 2.53 mL 12.63 mL 25.25 mL
1 mM 1.26 mL 6.31 mL 12.63 mL
5 mM 0.25 mL 1.26 mL 2.53 mL

*The above data is based on the productmolecular weight 792.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12592
Actions Inhibitor
M. Wt 792.01
Formula C43H69NO12
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 104987-12-4
Synonyms FK 520, FR 900520, FK520, FR900520
SMILES CC[[email protected]@H]1/C=C(/C[[email protected]@H](C[[email protected]@H]([[email protected]@H]2[[email protected]](C[[email protected]]([[email protected]@](O2)(C(=O)C(=O)N3CCCC[[email protected]]3C(=O)O[[email protected]@H]([[email protected]@H]([[email protected]](CC1=O)O)C)/C(=C/[[email protected]@H]4CC[[email protected]]([[email protected]@H](C4)OC)O)/C)O)C)OC)OC)C)\C

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