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Biological Activity
Asenapine(Org 5222) inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.99 mL | 174.97 mL | 349.93 mL |
| 0.5 mM | 7 mL | 34.99 mL | 69.99 mL |
| 1 mM | 3.5 mL | 17.5 mL | 34.99 mL |
| 5 mM | 0.7 mL | 3.5 mL | 7 mL |
*The above data is based on the productmolecular weight 285.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18010 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 65576-45-6 |
| Formula | C17H16ClNO |
| M. Wt | 285.77 |
| Purity | >98% |
| Synonyms | Org 5222, Org-5222, Org5222 |
| SMILES | ClC1=CC=C2OC3=CC=CC=C3[[email protected]@](C4)([H])[[email protected]](CN4C)([H])C2=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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