ASP8273 (Naquotinib)

Catalog No.: A14408

irreversible EGFR inhibitor

ASP8273 (Naquotinib)

ASP8273 (Naquotinib) Chemical Structure

CAS NO. 1448232-80-1

ASP8273 is an orally available, irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity.

Availability: In stock

Package Price Qty
2 mg
$80.00
5 mg
$135.00
10 mg
$225.00
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Biological Activity

ASP8273 is an orally available, irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity.
In vitro DMSO Warmed: 50 mg/mL (88.85 mM)
Water Insoluble
Ethanol Warmed: 96 mg/mL (170.6 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.77 mL 88.85 mL 177.71 mL
0.5 mM 3.55 mL 17.77 mL 35.54 mL
1 mM 1.78 mL 8.89 mL 17.77 mL
5 mM 0.36 mL 1.78 mL 3.55 mL

*The above data is based on the productmolecular weight 562.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14408
Actions Inhibitor
CAS No. 1448232-80-1
Formula C30H42N8O3
M. Wt 562.72
Solubility DMSO
Purity >98%
Synonyms Naquotinib (free base)
SMILES O=C(C1=NC(CC)=C(O[[email protected]]2CN(C(C=C)=O)CC2)N=C1NC3=CC=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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