Allitinib tosylate (AST-1306 TsOH, AST-6)

Catalog No.: A10062
EGFR inhibitor
AST-6 is a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, inhibits tumor growth both in vitro and in vivo
Grouped product items
Product Name Price Stock Qty
Allitinib tosylate 5mg
Special Price $120.00 Regular Price $150.00
In stock
Allitinib tosylate10mg
Special Price $192.00 Regular Price $240.00
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Allitinib tosylate 25mg
Special Price $416.00 Regular Price $520.00
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Allitinib tosylate50mg
Special Price $640.00 Regular Price $800.00
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Allitinib tosylate 10mM * 1mL in DMSO
Special Price $226.40 Regular Price $283.00
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Adooq Products cited in reputable paper
Biological Activity
Discription AST-6 is a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, inhibits tumor growth both in vitro and in vivo
Targets
Target Value
Product Information
Catalog Num A10062
Formula C24H18ClFN4O2.C7H8O3S
Molecular Weight 621.1
CAS Number 1050500-29-2
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 115 mg/mL (185.16 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% hydroxyethyl cellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.1 mL 80.5 mL 161 mL
0.5 mM 3.22 mL 16.1 mL 32.2 mL
1 mM 1.61 mL 8.05 mL 16.1 mL
5 mM 0.32 mL 1.61 mL 3.22 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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