AT-121 is a bifunctional agonist targeting nociception and the mu opioid receptor, demonstrating dissociation constants (Kis) of 3.67 and 16.49 nM, respectively. This compound exhibits significant antinociceptive and antiallodynic properties while maintaining a profile indicative of safety and non-addictiveness. AT-121 is of particular interest in pain management research, providing potential avenues for developing effective analgesics without the risks associated with traditional opioids.
AT-121 is a bifunctional agonist targeting nociception and the mu opioid receptor, demonstrating dissociation constants (Kis) of 3.67 and 16.49 nM, respectively. This compound exhibits significant antinociceptive and antiallodynic properties while maintaining a profile indicative of safety and non-addictiveness. AT-121 is of particular interest in pain management research, providing potential avenues for developing effective analgesics without the risks associated with traditional opioids.
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