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Publications citing Adooq Products
Chemical Information
| Catalog Num | A11313 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 418.7 |
| Formula | C16H17Cl2N5O2.HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 902135-91-5 |
| Synonyms | AT 7519, AT-7519 |
| SMILES code | C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl.Cl |
| Chemical Name | N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide hydrochloride |
Description |
AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Targets |
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| Solubility (25°C) * | In vitro | DMSO | 10 mg/mL (26.16 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.88 mL | 119.42 mL | 238.83mL |
| 0.5 mM | 4.78 mL | 23.88 mL | 47.77 mL |
| 1 mM | 2.39 mL | 11.94 mL | 23.88 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
*The above data is based on the productmolecular weight 418.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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