Signaling Pathway
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| Discription | AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. | ||
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| Targets |
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| Catalog Num | A11313 |
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| Formula | C16H17Cl2N5O2.HCl |
| Molecular Weight | 418.7 |
| CAS Number | 902135-91-5 |
| SMILES | C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl.Cl |
| Synonyms | AT 7519, AT-7519 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 49 mg/mL (117.03 mM) | |
| Water | Warmed: 40 mg/mL (95.53 mM) | ||
| Ethanol | Warmed: 26 mg/mL (62.09 mM) | ||
| In vivo | Saline | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.88 mL | 119.42 mL | 238.83 mL |
| 0.5 mM | 4.78 mL | 23.88 mL | 47.77 mL |
| 1 mM | 2.39 mL | 11.94 mL | 23.88 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
