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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15005 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 496.27 |
| Formula | C18H18Cl2F3N5O4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1431697-85-6 |
| Synonyms | AT 7519 trifluoroacetate, AT-7519 trifluoroacetate |
| SMILES code | C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl.C(=O)(C(F)(F)F)O |
| Chemical Name | 4-[(2,6-dichlorobenzoyl)amino]-N-piperidin-4-yl-1H-pyrazole-5-carboxamide,2,2,2-trifluoroacetic acid |
Description |
AT7519 trifluoroacetate is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM, less potent to CDK3 and little active to CDK7. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.15 mL | 100.75 mL | 201.5mL |
| 0.5 mM | 4.03 mL | 20.15 mL | 40.3 mL |
| 1 mM | 2.02 mL | 10.08 mL | 20.15 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.03 mL |
*The above data is based on the productmolecular weight 496.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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