Biological Activity
AT7519 trifluoroacetate is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM, less potent to CDK3 and little active to CDK7.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.15 mL | 100.75 mL | 201.5 mL |
0.5 mM | 4.03 mL | 20.15 mL | 40.3 mL |
1 mM | 2.02 mL | 10.08 mL | 20.15 mL |
5 mM | 0.4 mL | 2.02 mL | 4.03 mL |
*The above data is based on the productmolecular weight 496.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15005 |
---|---|
Actions | Inhibitor |
CAS No. | 1431697-85-6 |
Formula | C18H18Cl2F3N5O4 |
M. Wt | 496.27 |
Purity | >98% |
Synonyms | AT 7519 trifluoroacetate, AT-7519 trifluoroacetate |
SMILES | C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl.C(=O)(C(F)(F)F)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
PD 0332991 HCl (Palbociclib)
PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activit…
Kenpaullone
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with …
Purvalanol A
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/…
BS-181
BS-181 is a potential anti-tumor agent as CDK7 inhibitor.
BMS-863233 (XL-413)
BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineopla…
R547
R547 is a novel, selective inhibitor of cell cycle and transcriptional cyclin dependent kinases (CDKs) (Ki = 1, 3, and 1 nM for CDK1, CDK2, …
AMG-925
AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.
PHA-793887
PHA-793887, a novel potent inhibitor of Cdk, target on kinds of cyclin-dependent kinase under low concentrations and poses high activity ag…
Keywords:buy AT7519 trifluoroacetate | AT7519 trifluoroacetate Supplier | purchase | cost | manufacturer | order | distributor | buy 1431697-85-6| 1431697-85-6 Supplier | purchase 1431697-85-6 | 1431697-85-6 cost | 1431697-85-6 manufacturer | order 1431697-85-6 | 1431697-85-6 distributor