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Atilmotin

Catalog No.: A61953
Motilin Receptor Agonist
Atilmotin is a selective motilin receptor agonist with a pKd value of 8.94. It enhances gastrointestinal motility by increasing lower esophageal sphincter (LES) and gastric pressures, making it a valuable tool for studying esophageal and gastric motility. This compound is particularly relevant for research applications focused on gastrointestinal disorders and the development of prokinetic agents.
Atilmotin 533927-56-9 Motilin Receptor Agonist
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Size Price Stock Qty
25mg
$1,275.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAtilmotin is a selective motilin receptor agonist with a pKd value of 8.94. It enhances gastrointestinal motility by increasing lower esophageal sphincter (LES) and gastric pressures, making it a valuable tool for studying esophageal and gastric motility. This compound is particularly relevant for research applications focused on gastrointestinal disorders and the development of prokinetic agents.
Product Information
Catalog NumA61953
FormulaC86H135N20O19+
Molecular Weight1753.11
CAS Number533927-56-9
Sequence{Phe(Me3)}-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Lys
Sequence shortening{Phe(Me3)}-VPIFTYGELQRLK
SMILESCC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)[N+](C)(C)C)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O |@:31|
SynonymsOHM 11638; BAX-ACC 1638; MOT 288
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GPCR/G Protein > Motilin Receptor (MLNR)