ATL444

Catalog No.: A57983
Adenosine Receptor Antagonist
ATL444 is a selective adenosine receptor antagonist that exhibits Ki values of 7.0 nM for the rA1AR receptor, 2.5 nM for rA2AAR, 61.8 nM for rA2BAR, and >1000 nM for rA3AR. This compound is valuable for research applications focused on the modulation of adenosine signaling pathways, which are implicated in various physiological processes and disease states. ATL444 can aid in elucidating the role of adenosine receptors in pharmacological studies, offering insights into their potential as therapeutic targets.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionATL444 is a selective adenosine receptor antagonist that exhibits Ki values of 7.0 nM for the rA1AR receptor, 2.5 nM for rA2AAR, 61.8 nM for rA2BAR, and >1000 nM for rA3AR. This compound is valuable for research applications focused on the modulation of adenosine signaling pathways, which are implicated in various physiological processes and disease states. ATL444 can aid in elucidating the role of adenosine receptors in pharmacological studies, offering insights into their potential as therapeutic targets.
Product Information
Catalog NumA57983
FormulaC17H19N5O
Molecular Weight309.37
CAS Number867054-13-5
SMILESC#CCN1C2=NC(C#C[C@]3(C[C@@H](CCC3)C)O)=NC(N)=C2N=C1
Useful Calculator

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