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- Lehmann M, .et al. Platelets Drive Thrombus Propagation in a Hematocrit and Glycoprotein VI-Dependent Manner in an In Vitro Venous Thrombosis Model, Arterioscler Thromb Vasc Biol, 2018, May;38(5):1052-1062 PMID: 29472230
Biological Activity
Atopaxar hydrobromide shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC values of 0.064 and 0.031 μM respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.43 mL | 82.16 mL | 164.33 mL |
| 0.5 mM | 3.29 mL | 16.43 mL | 32.87 mL |
| 1 mM | 1.64 mL | 8.22 mL | 16.43 mL |
| 5 mM | 0.33 mL | 1.64 mL | 3.29 mL |
*The above data is based on the productmolecular weight 608.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13813 |
|---|---|
| CAS No. | 474550-69-1 |
| Formula | C29H39BrFN3O5 |
| M. Wt | 608.54 |
| Purity | >98% |
| Synonyms | ER172594-06, E5555, ER17259406 |
| SMILES | CCOC1=C(C(=C2C(=C1)CN(C2=N)CC(=O)C3=CC(=C(C(=C3)N4CCOCC4)OC)C(C)(C)C)F)OCC.Br |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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