Atraric acid, known as Methyl atrarate, functions as a specific antagonist of androgen receptors (AR). This compound demonstrates significant anti-inflammatory and anticancer properties by downregulating the expression of the prostate-specific antigen gene in LNCaP and C4-2 cell lines. Additionally, atraric acid inhibits nitric oxide synthesis and cytokine production while suppressing the MAPK-NFκB signaling pathway. Its utility in research extends to investigations of prostate diseases and inflammatory conditions.
Atraric acid, known as Methyl atrarate, functions as a specific antagonist of androgen receptors (AR). This compound demonstrates significant anti-inflammatory and anticancer properties by downregulating the expression of the prostate-specific antigen gene in LNCaP and C4-2 cell lines. Additionally, atraric acid inhibits nitric oxide synthesis and cytokine production while suppressing the MAPK-NFκB signaling pathway. Its utility in research extends to investigations of prostate diseases and inflammatory conditions.
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