AUT1

Catalog No.: A18648

Kv3 potassium channel modulator

AUT1

AUT1 Chemical Structure

CAS NO. 1311136-84-1

AUT1 is a Kv3 potassium channel modulator with pEC50s of 5.33 and 5.31 for human recombinant Kv3.1b and Kv3.2a, respectively, exhibits 10-fold lower potency at human recombinant Kv3.3 channel (pEC50, 4.5).

Availability: In stock

Package Price Qty
5 mg
$420.00
10 mg
$700.00
50 mg
$2,100.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AUT1 is a Kv3 potassium channel modulator with pEC50s of 5.33 and 5.31 for human recombinant Kv3.1b and Kv3.2a, respectively, exhibits 10-fold lower potency at human recombinant Kv3.3 channel (pEC50, 4.5).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.29 mL 146.47 mL 292.94 mL
0.5 mM 5.86 mL 29.29 mL 58.59 mL
1 mM 2.93 mL 14.65 mL 29.29 mL
5 mM 0.59 mL 2.93 mL 5.86 mL

*The above data is based on the productmolecular weight 341.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18648
Actions Modulator
CAS No. 1311136-84-1
Formula C18H19N3O4
M. Wt 341.37
Purity >98%
Synonyms AUT-1; AUT 1; AUT1
SMILES O=C1N(C2=CC=C(OC3=CC=C(C)C(OC)=C3)N=C2)C([[email protected]@H](CC)N1)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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