αvβ1 integrin-IN-2 is a highly effective inhibitor of integrins αvβ1 and α5β1, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. This compound also demonstrates inhibitory activity against additional integrins, including IC50s of 380 nM for αvβ3, 280 nM for αvβ5, 230 nM for αvβ6, and 87 nM for αvβ8, as determined by the SPRA assay. αvβ1 integrin-IN-2 is valuable for research applications focused on integrin-mediated signaling pathways and cell adhesion processes.
αvβ1 integrin-IN-2 is a highly effective inhibitor of integrins αvβ1 and α5β1, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. This compound also demonstrates inhibitory activity against additional integrins, including IC50s of 380 nM for αvβ3, 280 nM for αvβ5, 230 nM for αvβ6, and 87 nM for αvβ8, as determined by the SPRA assay. αvβ1 integrin-IN-2 is valuable for research applications focused on integrin-mediated signaling pathways and cell adhesion processes.
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