Axelopran is a potent opioid receptor antagonist that exhibits high affinity for human recombinant μ (pKi 9.8), δ (pKi 8.8) receptors, as well as the guinea pig κ receptor (pKi 9.9). This compound is primarily utilized in analgesic research and studies involving opioid receptor modulation. Its antagonistic properties make it valuable for investigating pain pathways and potential therapeutic applications in opioid overdose and addiction.
Axelopran is a potent opioid receptor antagonist that exhibits high affinity for human recombinant μ (pKi 9.8), δ (pKi 8.8) receptors, as well as the guinea pig κ receptor (pKi 9.9). This compound is primarily utilized in analgesic research and studies involving opioid receptor modulation. Its antagonistic properties make it valuable for investigating pain pathways and potential therapeutic applications in opioid overdose and addiction.
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