AZ191

Catalog No.: A14314

DYRK inhibitor

AZ191

AZ191 Chemical Structure

CAS NO. 1594092-37-1

AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2.

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$250.00
10mM * 1mL in DMSO
$66.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2.
Targets
Dyrk1B (Cell-free assay) DYRK1A (Cell-free assay) DYRK2 (Cell-free assay)
17 nM88 nM1890 nM
In vitro DMSO 86 mg/mL (200.22 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (2.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.28 mL 116.41 mL 232.82 mL
0.5 mM 4.66 mL 23.28 mL 46.56 mL
1 mM 2.33 mL 11.64 mL 23.28 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 429.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14314
Actions Inhibitor
M. Wt 429.52
Formula C24H27N7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1594092-37-1
Synonyms AZ 191, AZ-191
SMILES CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=CC(=N3)C4=CN(C5=C4C=CN=C5)C)OC

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy AZ191 | AZ191 Supplier | purchase AZ191 | AZ191 cost | AZ191 manufacturer | order AZ191 | AZ191 distributor | buy 1594092-37-1| 1594092-37-1 Supplier | purchase 1594092-37-1 | 1594092-37-1 cost | 1594092-37-1 manufacturer | order 1594092-37-1 | 1594092-37-1 distributor
Rewards