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AZ505 ditrifluoroacetate is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 uM) with potential anticancer activity, >600 fold than SMYD3(IC50>83.3 uM); DOT1L(IC50>83.3 uM);EZH2(IC50>83.3 uM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.41 mL | 62.07 mL | 124.13 mL |
| 0.5 mM | 2.48 mL | 12.41 mL | 24.83 mL |
| 1 mM | 1.24 mL | 6.21 mL | 12.41 mL |
| 5 mM | 0.25 mL | 1.24 mL | 2.48 mL |
*The above data is based on the productmolecular weight 805.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13169 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 805.59 |
| Formula | C33H40Cl2F6N4O8 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1035227-44-1 |
| Synonyms | AZ 505 ditrifluoroacetate, AZ-505 ditrifluoroacetate |
| SMILES | ClC1=C(Cl)C=C(CCNCCC(N(C2CCCCC2)CCNCCC3=C4C(N=C(O)CO4)=C(O)C=C3)=O)C=C1.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O |
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