AZD 7545

Catalog No.: A14157

PDHK inhibitor

AZD 7545

AZD 7545 Chemical Structure

CAS NO. 252017-04-2

AZD7545 is a novel, selective small-molecule inhibitor of PDHK2 (PDH kinase2) with an IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $170.00

Special Price $136.00

10 mg

Regular Price: $280.00

Special Price $224.00

25 mg

Regular Price: $480.00

Special Price $384.00

10mM * 1mL in DMSO
$210.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

AZD7545 is a novel, selective small-molecule inhibitor of PDHK2 (PDH kinase2) with an IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 respectively.
Targets
PDHK2 PDHK1
6.4 nM36.8 nM
In vitro DMSO 95 mg/mL (198.38 mM)
Water <1 mg/mL (<1 mM)
Ethanol 95 mg/mL (198.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.88 mL 104.41 mL 208.82 mL
0.5 mM 4.18 mL 20.88 mL 41.76 mL
1 mM 2.09 mL 10.44 mL 20.88 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14157
Actions Inhibitor
M. Wt 478.87
Formula C19H18ClF3N2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 252017-04-2
Synonyms AZD-7545,AZD7545
SMILES C[[email protected]@](C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O

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