AZD-8529

Catalog No.: A20045
mGluR2 modulator
AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
Grouped product items
Product Name Price Stock Qty
AZD-8529 1mg
$320.00
In stock
AZD-8529 5mg
$960.00
In stock
AZD-8529 10mg
$1,600.00
In stock
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Biological Activity
Discription AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
Targets
Target Value
Product Information
Catalog Num A20045
Formula C24H24F3N5O3
Molecular Weight 487.47
CAS Number 1092453-15-0
SMILES O=C1C2=C(C)C=C(C3=NC(CN4CCNCC4)=NO3)C=C2CN1CC5=CC=C(OC(F)(F)F)C=C5
Synonyms AZD8529, AZD 8529
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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