Catalog No.: A16839

ERK inhibitor


AZD0364 Chemical Structure

CAS NO. 2097416-76-5

AZD0364 is a pre-clinical ERK1/2 inhibitor with an IC50 of 0.6 nM for ERK2.

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Biological Activity

AZD0364 is a pre-clinical ERK1/2 inhibitor with an IC50 of 0.6 nM for ERK2.
In vitro DMSO 93 mg/mL (188.07 mM)
Water Insoluble
Ethanol 93 mg/mL (188.07 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.11 mL 202.22 mL
0.5 mM 4.04 mL 20.22 mL 40.44 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 494.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16839
Actions Inhibitor
CAS No. 2097416-76-5
Formula C24H24F2N8O2
M. Wt 494.5
Purity >98%
Synonyms AZD 0364, AZD-0364
SMILES O=C1C2=NC(C3=NC(NC4=CC=NN4C)=NC=C3C)=CN2C[[email protected]](COC)N1CC5=CC=C(F)C(F)=C5

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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