AZD3759

Catalog No.: A15551

EGFR inhibitor

AZD3759 Chemical Structure

CAS NO. 1626387-80-1

AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR). It binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR.

Availability: In stock

Package Price Qty
10 mg
$80.00
25 mg
$120.00
50 mg
$150.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR). It binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR.
Targets
EGFR (L858R) EGFR (exon 19Del) EGFR (WT)
0.2 nM0.2 nM0.3 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.74 mL 108.72 mL 217.44 mL
0.5 mM 4.35 mL 21.74 mL 43.49 mL
1 mM 2.17 mL 10.87 mL 21.74 mL
5 mM 0.43 mL 2.17 mL 4.35 mL

*The above data is based on the productmolecular weight 459.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15551
Actions Inhibitor
M. Wt 459.9
Formula C22H23ClFN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1626387-80-1
Synonyms AZD 3759
SMILES CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C

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