AZD5153 6-Hydroxy-2-naphthoic acid

Catalog No.: A21852

BET/BRD4 bromodomain inhibitor

AZD5153 6-Hydroxy-2-naphthoic acid

AZD5153 6-Hydroxy-2-naphthoic acid Chemical Structure

CAS NO. 1869912-40-2

AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.

Availability: In stock

Package Price Qty
5 mg
$130.00
10 mg
$223.00
50 mg
$662.00
100 mg
$1,325.00
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Biological Activity

AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.98 mL 74.88 mL 149.76 mL
0.5 mM 3 mL 14.98 mL 29.95 mL
1 mM 1.5 mL 7.49 mL 14.98 mL
5 mM 0.3 mL 1.5 mL 3 mL

*The above data is based on the productmolecular weight 667.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21852
Actions Inhibitor
M. Wt 667.75
Formula C36H41N7O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1869912-40-2
Synonyms AZD-5153 HNT salt, AZD5153, AZD 5153
SMILES O=C(C1=CC=C2C=C(O)C=CC2=C1)O.O=C3N(C)CCN(CCOC4=CC=C(C5CCN(C6=NN7C(C=C6)=NN=C7OC)CC5)C=C4)[[email protected]@H]3C

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