AZD5438

Name: AZD5438
Brand: Adooq Bioscience
SKU: A11105
Rating: 100 (268 reviews)

Catalog No.: A11105

CDK inhibitor

AZD5438 Chemical Structure

CAS NO. 602306-29-6

AZD5438 is a potent inhibitor of cyclin-dependent kinase (CDK) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectively).

Availability: In stock

Package	Price	Qty
10 mg	Regular Price: $50.00 Special Price $40.00
50 mg	Regular Price: $150.00 Special Price $120.00
100 mg	Regular Price: $250.00 Special Price $200.00
200 mg	Regular Price: $400.00 Special Price $320.00
10mM * 1mL in DMSO	Regular Price: $78.00 Special Price $62.40
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Biological Activity

AZD5438 is a potent inhibitor of cyclin-dependent kinase (CDK) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectively).

Solubility *

In vitro	DMSO	68 mg/mL (183.06 mM)
	Water	Insoluble
	Ethanol	68 mg/mL (183.06 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.92 mL	134.59 mL	269.18 mL
0.5 mM	5.38 mL	26.92 mL	53.84 mL
1 mM	2.69 mL	13.46 mL	26.92 mL
5 mM	0.54 mL	2.69 mL	5.38 mL

*The above data is based on the productmolecular weight 371.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11105
Actions	Inhibitor
CAS No.	602306-29-6
Formula	C18H21N5O2S
M. Wt	371.5
Purity	>98%
Synonyms	AZD-5438
SMILES	CC1=NC=C(N1C(C)C)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)C
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.