AZD5582

Catalog No.: A21735

IAPs antagonist

AZD5582

AZD5582 Chemical Structure

CAS NO. 1258392-53-8

AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$107.00
10 mg
$184.00
50 mg
$547.00
100 mg
$1,095.00
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Biological Activity

AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.
In vitro DMSO 98 mg/mL (96.52 mM)
Water 98 mg/mL (96.52 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.85 mL 49.25 mL 98.49 mL
0.5 mM 1.97 mL 9.85 mL 19.7 mL
1 mM 0.98 mL 4.92 mL 9.85 mL
5 mM 0.2 mL 0.98 mL 1.97 mL

*The above data is based on the productmolecular weight 1015.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21735
Actions Antagonist
CAS No. 1258392-53-8
Formula C58H78N8O8
M. Wt 1015.29
Purity >98%
Synonyms AZD 5582, AZD-5582
SMILES CN[[email protected]@H](C)C(N[[email protected]](C(N1[[email protected]](C(N[[email protected]]2C3=CC=CC=C3C[[email protected]]2OCC#CC#CCO[[email protected]]4[[email protected]@H](NC([[email protected]@H]5CCCN5C([[email protected]@H](NC([[email protected]](C)NC)=O)C6CCCCC6)=O)=O)C(C=CC=C7)=C7C4)=O)CCC1)=O)C8CCCCC8)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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