AZD8055

Catalog No.: A10114

mTOR Inhibitor

AZD8055

AZD8055 Chemical Structure

CAS NO. 1009298-09-2

AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $40.00

Special Price $32.00

25 mg

Regular Price: $80.00

Special Price $64.00

50 mg

Regular Price: $120.00

Special Price $96.00

100 mg

Regular Price: $180.00

Special Price $144.00

10mM * 1mL in DMSO
$78.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.
Targets
Target Value
mTOR(truncated)IC50: 0.13nM
mTOR(fulllength)IC50: 0.8nM
DNA-PKIC50: 1370nM
PI3KδIC50: 3200nM
PI3KαIC50: 3590nM
ATMIC50: 7350nM
PI3KγIC50: >14790nM
PI3KβIC50: 18900nM
In vitro DMSO 50 mg/mL heating (107.4 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (6.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.41 mL 214.82 mL
0.5 mM 4.3 mL 21.48 mL 42.96 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10114
Actions Inhibitor
M. Wt 465.5
Formula C25H31N5O4
Solubility DMSO>93mg/mL Water>2mg/mL Ethanol>15mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1009298-09-2
Synonyms AZD-8055
SMILES C[[email protected]]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOC[[email protected]@H]5C

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