AZD8055

Catalog No.: A10114
mTOR Inhibitor
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.
Grouped product items
Product Name Price Stock Qty
AZD8055 10mg
$40.00
In stock
AZD8055 25mg
$80.00
In stock
AZD8055 50mg
$120.00
In stock
AZD8055 100mg
$180.00
In stock
AZD8055 10mM * 1mL in DMSO
$78.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AZD8055 has been cited by 3 publications
  • L. M. C. Koene, .et al. , ACTN, 2019, June PMID: 31353861
  • Helga Weber, .et al. , Oncotarget, 2015, Oct 13; 6(31): 31877-31888 PMID: 26397134
  • Kentaro Hirose, .et al. , BMC Dev Biol, 2014, 14: 42. PMID: 25480380
  • Biological Activity
    Discription AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.
    Targets
    Target Value
    Product Information
    Catalog Num A10114
    Formula C25H31N5O4
    Molecular Weight 465.5
    CAS Number 1009298-09-2
    SMILES C[C@H]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOC[C@@H]5C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 49 mg/mL (105.25 mM)
    Water Insoluble
    Ethanol 3 mg/mL (6.44 mM)
    In vivo 4% DMSO+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.48 mL 107.41 mL 214.82 mL
    0.5 mM 4.3 mL 21.48 mL 42.96 mL
    1 mM 2.15 mL 10.74 mL 21.48 mL
    5 mM 0.43 mL 2.15 mL 4.3 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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