AZD8055

Catalog No.: A10114
mTOR Inhibitor
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.
Grouped product items
Size Price Stock Qty
5mg
$30.00
In stock
10mg
$35.00
In stock
25mg
$70.00
In stock
50mg
$85.00
In stock
100mg
$145.00
In stock
200mg
$275.00
In stock
10mM * 1mL in DMSO
$45.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AZD8055 has been cited by 3 publications
  • L. M. C. Koene, .et al. , ACTN, 2019, June PMID: 31353861
  • Helga Weber, .et al. , Oncotarget, 2015, Oct 13; 6(31): 31877-31888 PMID: 26397134
  • Kentaro Hirose, .et al. , BMC Dev Biol, 2014, 14: 42. PMID: 25480380
  • Biological Activity
    Discription AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10114
    Formula C25H31N5O4
    Molecular Weight 465.5
    CAS Number 1009298-09-2
    SMILES C[C@H]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOC[C@@H]5C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 49 mg/mL (105.25 mM)
    Water Insoluble
    Ethanol 3 mg/mL (6.44 mM)
    In vivo 4% DMSO+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.48 mL 107.41 mL 214.82 mL
    0.5 mM 4.3 mL 21.48 mL 42.96 mL
    1 mM 2.15 mL 10.74 mL 21.48 mL
    5 mM 0.43 mL 2.15 mL 4.3 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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