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Biological Activity
AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist.
Targets
| estrogen receptor | ||||
| In vitro | DMSO | 77 mg/mL (174.02 mM) | |
| Water | Insoluble | ||
| Ethanol | 77 mg/mL (174.02 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.6 mL | 113 mL | 226 mL |
| 0.5 mM | 4.52 mL | 22.6 mL | 45.2 mL |
| 1 mM | 2.26 mL | 11.3 mL | 22.6 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15822 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1639042-08-2 |
| Formula | C25H25F3N2O2 |
| M. Wt | 442.48 |
| Purity | >98% |
| Synonyms | AZD-9496, AZD 9496 |
| SMILES | CC1CC2=C(C(N1CC(C)(C)F)C3=C(C=C(C=C3F)C=CC(=O)O)F)NC4=CC=CC=C24 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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