Signaling Pathway
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| Discription | Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression in patients with mild Alzheimer??s disease (AD). Azeliragon also can cross the blood-brain barrier (BBB). |
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| Catalog Num | A20622 |
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| Formula | C32H38ClN3O2 |
| Molecular Weight | 532.12 |
| CAS Number | 603148-36-3 |
| SMILES | ClC1=CC=C(C=C1)OC2=CC=C(C=C2)N3C(CCCC)=NC(C(C=C4)=CC=C4OCCCN(CC)CC)=C3 |
| Synonyms | TTP488, TTP 488, TTP-488; PF-04494700, PF 04494700, PF04494700 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 90 mg/mL (169.13 mM) | |
| Water | Insoluble | ||
| Ethanol | 90 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.79 mL | 93.96 mL | 187.93 mL |
| 0.5 mM | 3.76 mL | 18.79 mL | 37.59 mL |
| 1 mM | 1.88 mL | 9.4 mL | 18.79 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
