Azide-PEG5-Tos is a cleavable five-unit polyethylene glycol (PEG) linker designed for the synthesis of antibody-drug conjugates (ADCs). It features an azide moiety that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules. This reagent is essential for the development of targeted therapeutics and advancing research in bioconjugation strategies.
Azide-PEG5-Tos is a cleavable five-unit polyethylene glycol (PEG) linker designed for the synthesis of antibody-drug conjugates (ADCs). It features an azide moiety that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules. This reagent is essential for the development of targeted therapeutics and advancing research in bioconjugation strategies.
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