Azidoethyl-SS-propionic NHS ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features an azide functional group, enabling it to participate in click chemistry reactions, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalities, making it a versatile tool for bioconjugation applications in chemical biology and targeted therapeutics.
Azidoethyl-SS-propionic NHS ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features an azide functional group, enabling it to participate in click chemistry reactions, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalities, making it a versatile tool for bioconjugation applications in chemical biology and targeted therapeutics.
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