Fig. 1 · Structure
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Azilsartan-d4
Stable Isotope
Azilsartan-d4 is a deuterium-labeled analog of Azilsartan, a potent and selective antagonist of the angiotensin II type 1 receptor (AT1). This stable isotope plays a key role in tracing and quantifying the pharmacokinetics of Azilsartan in biological systems. Additionally, Azilsartan promotes reactive oxygen species (ROS) formation and apoptosis in HepG2 cancer cells, demonstrating potential neuroprotective and anticancer properties. It is applicable in research focused on hypertension and stroke mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1794817-45-0 |
| Applications | Stable Isotope |
| Formula | C25H16D4N4O5 |
| Molecular Weight | 460.47 |
| Synonyms | TAK-536-d4 |
| SMILES | CCOC1=NC2=CC=CC(C(O)=O)=C2N1CC3=C([2H])C([2H])=C(C4=C(C5=NOC(N5)=O)C=CC=C4)C([2H])=C3[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.