Azure B is a potent and selective reversible inhibitor of monoamine oxidase A (MAO-A), exhibiting IC50 values of 11 nM for recombinant human MAO-A and 968 nM for MAO-B. As the major metabolite of Methylene blue, Azure B plays a crucial role in the synthesis of Azure eosin stains, commonly used for blood smear staining. This compound also demonstrates significant antidepressant-like effects, making it a valuable reagent for research in neuropharmacology and the study of mood disorders.
Azure B is a potent and selective reversible inhibitor of monoamine oxidase A (MAO-A), exhibiting IC50 values of 11 nM for recombinant human MAO-A and 968 nM for MAO-B. As the major metabolite of Methylene blue, Azure B plays a crucial role in the synthesis of Azure eosin stains, commonly used for blood smear staining. This compound also demonstrates significant antidepressant-like effects, making it a valuable reagent for research in neuropharmacology and the study of mood disorders.
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