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β-Amyloid (17-40)

Catalog No.: A78294
Amyloid-β Fragment
β-Amyloid (17-40) is a fragment of the Amyloid-β peptide that primarily targets neurotoxic pathways associated with Alzheimer's disease. This compound has demonstrated notable neurotoxic effects in SH-SY5Y and IMR-32 neuronal cell lines. Due to its biological activity, β-Amyloid (17-40) is a valuable tool for investigating the mechanisms underlying neurological diseases and for developing potential therapeutic strategies.
β-Amyloid (17-40) 156790-69-1 Amyloid-β Fragment
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ-Amyloid (17-40) is a fragment of the Amyloid-β peptide that primarily targets neurotoxic pathways associated with Alzheimer's disease. This compound has demonstrated notable neurotoxic effects in SH-SY5Y and IMR-32 neuronal cell lines. Due to its biological activity, β-Amyloid (17-40) is a valuable tool for investigating the mechanisms underlying neurological diseases and for developing potential therapeutic strategies.
Product Information
Catalog NumA78294
FormulaC110H178N26O31S
Molecular Weight2392.81
CAS Number156790-69-1
SequenceLeu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Sequence shorteningLVFFAEDVGSNKGAIIGLMVGGVV
SMILES[C@H](CC1=CC=CC=C1)(C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)C(C)C)=O)=O)=O)C(C)C)=O)CCSC)=O)CC(C)C)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C)=O)=O)CCCCN)=O)CC(N)=O)=O)CO)=O)=O)C(C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)NC([C@@H](NC([C@H](CC(C)C)N)=O)C(C)C)=O
SynonymsAβ(17-40)
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Neuronal Signaling > Amyloid-β