β-Amyloid (22-40)

Catalog No.: A78383
Amyloid-β
β-Amyloid (22-40) is a peptide fragment derived from the amyloid precursor protein, primarily targeting amyloid-β. This fragment is pivotal in the study of amyloid aggregation and plaque formation associated with Alzheimer's disease. Its application in research includes elucidating amyloid pathophysiology and screening potential therapeutic compounds for neurodegenerative disorders.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ-Amyloid (22-40) is a peptide fragment derived from the amyloid precursor protein, primarily targeting amyloid-β. This fragment is pivotal in the study of amyloid aggregation and plaque formation associated with Alzheimer's disease. Its application in research includes elucidating amyloid pathophysiology and screening potential therapeutic compounds for neurodegenerative disorders.
Product Information
Catalog NumA78383
FormulaC78H135N21O26S
Molecular Weight1815.10
CAS Number1206779-25-0
Sequence shorteningEDVGSNKGAIIGLMVGGVV
SMILES[C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)CC(O)=O)=O)[C@H](C)C)=O)=O)CO)=O)CC(N)=O)=O)CCCCN)=O)=O)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)=O)CC(C)C)=O)(C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)[C@@H](C)C)=O)=O)=O)C(C)C)=O)CCSC
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