β Amyloid (3-40)

Catalog No.: A78363
Aβ Fragment
β Amyloid (3-40) is a fragment of amyloid-beta (Aβ) that plays a critical role in Alzheimer's disease pathology. This peptide is involved in the aggregation processes that lead to the formation of amyloid plaques in the brain. Research applications include studies of neurodegeneration, cellular toxicity, and the molecular mechanisms underlying Alzheimer's disease. Its use provides insights into potential therapeutic targets and pathways for intervention in age-related cognitive decline.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ Amyloid (3-40) is a fragment of amyloid-beta (Aβ) that plays a critical role in Alzheimer's disease pathology. This peptide is involved in the aggregation processes that lead to the formation of amyloid plaques in the brain. Research applications include studies of neurodegeneration, cellular toxicity, and the molecular mechanisms underlying Alzheimer's disease. Its use provides insights into potential therapeutic targets and pathways for intervention in age-related cognitive decline.
Product Information
Catalog NumA78363
FormulaC187H285N51O54S
Molecular Weight4143.64
CAS Number157884-70-3
SequenceGlu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Sequence shorteningEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
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