B-Raf IN 1

Catalog No.: A21055

B-Raf kinase inhibitor

B-Raf IN 1

B-Raf IN 1 Chemical Structure

CAS NO. 950736-05-7

B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM.

Availability: In stock

Package Price Qty
5 mg
$259.00
10 mg
$446.00
50 mg
$1,325.00
100 mg
$2,650.00
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Biological Activity

B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM.
In vitro DMSO 92 mg/mL (178.45 mM)
Water Insoluble
Ethanol 5 mg/mL (9.69 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.4 mL 96.99 mL 193.98 mL
0.5 mM 3.88 mL 19.4 mL 38.8 mL
1 mM 1.94 mL 9.7 mL 19.4 mL
5 mM 0.39 mL 1.94 mL 3.88 mL

*The above data is based on the productmolecular weight 515.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21055
Actions Inhibitor
CAS No. 950736-05-7
Formula C29H24F3N5O
M. Wt 515.53
Purity >98%
SMILES O=C(NC1=CC=CC(C2=CC=NC3=C(C4=CC=C(CN(C)C)C=C4)C=NN23)=C1)C5=CC=CC(C(F)(F)F)=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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