B-Raf IN 7 is a potent inhibitor of the B-Raf kinase, demonstrating an IC50 value of 110.23 nM. This compound has shown significant antitumor activity in various cancer cell lines, including colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela), and human prostate cancer (PC-3), with IC50 values ranging from 7.50 to 12.83 µM. B-Raf IN 7 is a valuable tool for research in cancer biology and therapeutic development targeting the RAS/RAF/MEK/ERK signaling pathway.
B-Raf IN 7 is a potent inhibitor of the B-Raf kinase, demonstrating an IC50 value of 110.23 nM. This compound has shown significant antitumor activity in various cancer cell lines, including colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela), and human prostate cancer (PC-3), with IC50 values ranging from 7.50 to 12.83 µM. B-Raf IN 7 is a valuable tool for research in cancer biology and therapeutic development targeting the RAS/RAF/MEK/ERK signaling pathway.
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