Bafetinib (INNO-406)

Name: Bafetinib (INNO-406)
SKU: A10119
Price: 75 USD
Rating: 5 (5 reviews)

Catalog No.: A10119

Bcr-Abl inhibitor

Adooq's Bafetinib (INNO-406) has been cited by 5 publications

Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Bafetinib (INNO-406) has been cited by 5 publications

Yusuke Kimata, .et al. , Life Sci Alliance, 2023, Feb 27;6(5):e202201657 PMID: 36849250

Li T, .et al. , Oncogene, 2018, Nov;37(47):6180-6194 PMID: 30013190

S. Dallari, .et al. , Nat Commun, 2017, 8: 14830 PMID: 28368000

Andrea Haerzschel, .et al. , Ann Hematol, 2016, 95(12): 1979-1988 PMID: 27542958

Magdalena Winiarska, .et al. , MAbs., 2014, 6(5): 1300-1313 PMID: 25517315

Biological Activity

Discription

Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.

Targets

Target	Value

Chemical Information

Catalog Num	A10119
Formula	C30H31F3N8O
Molecular Weight	576.6
CAS Number	859212-16-1
SMILES	CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CC[C@@H](C3)N(C)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CN=C5
Synonyms	NS-187
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	92 mg/mL (159.55 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose+0.2% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.34 mL	86.72 mL	173.43 mL
0.5 mM	3.47 mL	17.34 mL	34.69 mL
1 mM	1.73 mL	8.67 mL	17.34 mL
5 mM	0.35 mL	1.73 mL	3.47 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
Bafetinib 5mg	$75.00	In stock
Bafetinib 10mg	$130.00	In stock
Bafetinib 50mg	$390.00	In stock
Bafetinib 100mg	$480.00	In stock
*Bafetinib (INNO-406) 10mM 1mL in DMSO**	$174.00	In stock