Bafetinib (INNO-406)

Catalog No.: A10119

Bcr-Abl inhibitor

Bafetinib (INNO-406)

Bafetinib (INNO-406) Chemical Structure

CAS NO. 859212-16-1

Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $75.00

Special Price $60.00

10 mg

Regular Price: $130.00

Special Price $104.00

50 mg

Regular Price: $390.00

Special Price $312.00

100 mg

Regular Price: $480.00

Special Price $384.00

10mM * 1mL in DMSO
$174.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.
Targets
Abl (Cell-free assay) Lyn (Cell-free assay)
5.8 nM19 nM
In vitro (25°C) DMSO 100 mg/mL (173.42 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.34 mL 86.72 mL 173.43 mL
0.5 mM 3.47 mL 17.34 mL 34.69 mL
1 mM 1.73 mL 8.67 mL 17.34 mL
5 mM 0.35 mL 1.73 mL 3.47 mL

*The above data is based on the productmolecular weight 576.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10119
Actions Inhibitor
M. Wt 576.6
Formula C30H31F3N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 859212-16-1
Synonyms NS-187
SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CC[[email protected]@H](C3)N(C)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CN=C5

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