BAY 1000394 (Roniciclib)

Catalog No.: A12742

CDK inhibitor

BAY 1000394 (Roniciclib)

BAY 1000394 (Roniciclib) Chemical Structure

CAS NO. 1223498-69-8

BAY 1000394 is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity.

Availability: Out of stock

Package Price
5 mg
$350.00
10 mg
$650.00
25 mg
$1,200.00
50 mg
$2,000.00
Custom Size Get quote
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Marzia Ognibene, .et al. Roniciclib down-regulates stemness and inhibits cell growth by inducing nucleolar stress in neuroblastoma, Sci Rep, 2020, 10: 12902 PMID: 32737364
  • Xinan (Holly) Yang, .et al. A c-Myc-regulated stem cell-like signature in high-risk neuroblastoma: A systematic discovery (Target neuroblastoma ESC-like signature), Sci Rep, 2017, 7: 41 PMID: 28246384

Biological Activity

BAY 1000394 is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.23 mL 116.16 mL 232.32 mL
0.5 mM 4.65 mL 23.23 mL 46.46 mL
1 mM 2.32 mL 11.62 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL

*The above data is based on the productmolecular weight 430.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12742
Actions Inhibitor
CAS No. 1223498-69-8
Formula C18H21F3N4O3S
M. Wt 430.44
Purity >98%
Synonyms BAY10-00394; BAY1000394
SMILES C[[email protected]]([[email protected]@H](C)OC1=NC(=NC=C1C(F)(F)F)NC2=CC=C(C=C2)S(=N)(=O)C3CC3)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy BAY 1000394 (Roniciclib) | BAY 1000394 (Roniciclib) Supplier | purchase | cost | manufacturer | order | distributor | buy 1223498-69-8| 1223498-69-8 Supplier | purchase 1223498-69-8 | 1223498-69-8 cost | 1223498-69-8 manufacturer | order 1223498-69-8 | 1223498-69-8 distributor
Rewards