BAY-7081 is a potent and selective inhibitor of phosphodiesterase 9A (PDE9A), demonstrating an IC50 value of 15 nM. This cyanopyridone-based compound exhibits robust oral bioavailability and solubility, making it a valuable tool for investigating the role of PDE9A in various biological processes. Its application in research includes studies on neurodegenerative diseases and cognitive function, where modulation of the cyclic GMP signaling pathway may be beneficial.
BAY-7081 is a potent and selective inhibitor of phosphodiesterase 9A (PDE9A), demonstrating an IC50 value of 15 nM. This cyanopyridone-based compound exhibits robust oral bioavailability and solubility, making it a valuable tool for investigating the role of PDE9A in various biological processes. Its application in research includes studies on neurodegenerative diseases and cognitive function, where modulation of the cyclic GMP signaling pathway may be beneficial.
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