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- Rita Paolini, .et al. Transcriptional regulation of glucose transporters in human oral squamous cell carcinoma cells, J Oral Pathol Med, 2022, Sep;51(8):679-683 PMID: 35920070
Biological Activity
BAY-876 is a potent and Selective GLUT1 Inhibitor. BAY-876 showed good metabolic stability in vitro and high oral bioavailability in vivo.
| In vitro | DMSO | Warmed: 88 mg/mL (177.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 3 mg/mL (6.04 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.14 mL | 100.72 mL | 201.44 mL |
| 0.5 mM | 4.03 mL | 20.14 mL | 40.29 mL |
| 1 mM | 2.01 mL | 10.07 mL | 20.14 mL |
| 5 mM | 0.4 mL | 2.01 mL | 4.03 mL |
*The above data is based on the productmolecular weight 496.4256. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17216 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1799753-84-6 |
| Formula | C24H16F4N6O2 |
| M. Wt | 496.4256 |
| Purity | >98% |
| Synonyms | BAY 876, BAY876 |
| SMILES | O=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C=C4)C#N)N=C3C(F)(F)F)=O)=C1)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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