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BAY-876

Catalog No.: A17216

GLUT1 Inhibitor

BAY-876

BAY-876 Chemical Structure

CAS NO. 1799753-84-6

BAY-876 is a potent and Selective GLUT1 Inhibitor. BAY-876 showed good metabolic stability in vitro and high oral bioavailability in vivo.

Availability: In stock

Package Price Qty
2 mg
$90.00
5 mg
$110.00
10 mg
$160.00
50 mg
$480.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Rita Paolini, .et al. Transcriptional regulation of glucose transporters in human oral squamous cell carcinoma cells, J Oral Pathol Med, 2022, Sep;51(8):679-683 PMID: 35920070

Biological Activity

BAY-876 is a potent and Selective GLUT1 Inhibitor. BAY-876 showed good metabolic stability in vitro and high oral bioavailability in vivo.
In vitro DMSO Warmed: 88 mg/mL (177.26 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL (6.04 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.14 mL 100.72 mL 201.44 mL
0.5 mM 4.03 mL 20.14 mL 40.29 mL
1 mM 2.01 mL 10.07 mL 20.14 mL
5 mM 0.4 mL 2.01 mL 4.03 mL

*The above data is based on the productmolecular weight 496.4256. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17216
Actions Inhibitor
CAS No. 1799753-84-6
Formula C24H16F4N6O2
M. Wt 496.4256
Purity >98%
Synonyms BAY 876, BAY876
SMILES O=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C=C4)C#N)N=C3C(F)(F)F)=O)=C1)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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