Bazedoxifene hydrochloride is a nonsteroidal selective estrogen receptor modulator (SERM) that targets estrogen receptors ERα and ERβ, with IC50 values of 23 nM and 99 nM, respectively. This compound exhibits significant biological activity by inhibiting IL-6/GP130 protein-protein interactions, making it valuable in osteoporosis research. Additionally, Bazedoxifene hydrochloride is also utilized in studies related to pancreatic cancer, providing insights into its therapeutic potential and mechanisms of action.
Bazedoxifene hydrochloride is a nonsteroidal selective estrogen receptor modulator (SERM) that targets estrogen receptors ERα and ERβ, with IC50 values of 23 nM and 99 nM, respectively. This compound exhibits significant biological activity by inhibiting IL-6/GP130 protein-protein interactions, making it valuable in osteoporosis research. Additionally, Bazedoxifene hydrochloride is also utilized in studies related to pancreatic cancer, providing insights into its therapeutic potential and mechanisms of action.
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