BBDDL2059 is a selective covalent inhibitor targeting the histone methyltransferase EZH2, demonstrating an IC50 of 1.5 nM against the EZH2-Y641F mutation. This compound effectively inhibits lymphoma cell proliferation at nanomolar concentrations, making it a valuable tool for anticancer research. BBDDL2059 is suitable for investigations into the mechanistic roles of EZH2 in cancer biology and therapeutic development.
BBDDL2059 is a selective covalent inhibitor targeting the histone methyltransferase EZH2, demonstrating an IC50 of 1.5 nM against the EZH2-Y641F mutation. This compound effectively inhibits lymphoma cell proliferation at nanomolar concentrations, making it a valuable tool for anticancer research. BBDDL2059 is suitable for investigations into the mechanistic roles of EZH2 in cancer biology and therapeutic development.
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