Becatecarin

Catalog No.: A57219
topoisomerases I/II inhibitor
Becatecarin is an analog of rebeccamycin that primarily targets topoisomerases I and II. This compound exerts antitumor effects by intercalating into DNA, consequently inhibiting the catalytic activity of these enzymes. Due to its mechanism of action, Becatecarin is valuable in cancer research, particularly in studies exploring DNA damage and repair pathways.
Grouped product items
Size Price Stock Qty
250µg
$400.00
In stock
1mg
$1,185.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBecatecarin is an analog of rebeccamycin that primarily targets topoisomerases I and II. This compound exerts antitumor effects by intercalating into DNA, consequently inhibiting the catalytic activity of these enzymes. Due to its mechanism of action, Becatecarin is valuable in cancer research, particularly in studies exploring DNA damage and repair pathways.
Product Information
Catalog NumA57219
FormulaC33H34Cl2N4O7
Molecular Weight669.55
CAS Number119673-08-4
SMILESClC1=CC=CC2=C1NC3=C2C4=C(C(N(CCN(CC)CC)C4=O)=O)C5=C3N([C@@H]6O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]6O)C7=C(Cl)C=CC=C75
SynonymsNSC 655649; BMS 181176; BMY 27557
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