Bendamustine-d8

Catalog No.: A32617
Stable Isotope
Bendamustine-d8 is a deuterium-labeled derivative of Bendamustine, a purine analogue known for its powerful DNA cross-linking ability. This stable isotope facilitates the study of cancer research by enabling the tracking of Bendamustine's metabolism and efficacy in various biological systems. Bendamustine exhibits significant alkylating, anticancer, and antimetabolite properties, activating DNA-damage stress responses and apoptosis pathways, making it a valuable reagent for investigating cancer treatment modalities.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBendamustine-d8 is a deuterium-labeled derivative of Bendamustine, a purine analogue known for its powerful DNA cross-linking ability. This stable isotope facilitates the study of cancer research by enabling the tracking of Bendamustine's metabolism and efficacy in various biological systems. Bendamustine exhibits significant alkylating, anticancer, and antimetabolite properties, activating DNA-damage stress responses and apoptosis pathways, making it a valuable reagent for investigating cancer treatment modalities.
Product Information
Catalog NumA32617
FormulaC16H13D8Cl2N3O2
Molecular Weight366.31
CAS Number1134803-33-0
SMILESCN1C2=CC=C(N(C([2H])([2H])C([2H])([2H])Cl)C([2H])([2H])C([2H])([2H])Cl)C=C2N=C1CCCC(O)=O
SynonymsSDX-105-d8 free base
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