Benzthiazide

Catalog No.: A17355

CA9 inhibitor

Benzthiazide

Benzthiazide Chemical Structure

CAS NO. 91-33-8

Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells.

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500 mg
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Biological Activity

Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.15 mL 115.76 mL 231.51 mL
0.5 mM 4.63 mL 23.15 mL 46.3 mL
1 mM 2.32 mL 11.58 mL 23.15 mL
5 mM 0.46 mL 2.32 mL 4.63 mL

*The above data is based on the productmolecular weight 431.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17355
Actions Inhibitor
CAS No. 91-33-8
Formula C15H14ClN3O4S3
M. Wt 431.94
Solubility DMSO
Purity >98%
Synonyms Benzthiazide; Benzothiazide; Dihydrex; Aquatag; Diucen; Exna; Edemax; Foven; Dytide
SMILES O=S(N=C1CSCC2=CC=CC=C2)(C3=CC(S(=O)(N)=O)=C(Cl)C=C3N1)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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