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DNA topoisomerase II inhibitor

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Catalog No. A13059

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Beta-Lapachone 10mg A13059-10

Regular Price: $55.00

Special Price: $49.50

Beta-Lapachone 25mg A13059-25

Regular Price: $110.00

Special Price: $99.00

Beta-Lapachone 50mg A13059-50

Regular Price: $200.00

Special Price: $180.00

Beta-Lapachone 100mg A13059-100

Regular Price: $380.00

Special Price: $342.00

Beta-Lapachone 10mM * 1mL in DMSO A13059-10mM-D

Regular Price: $75.00

Special Price: $67.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Beta-Lapachone is a selective DNA topoisomerase I inhibitor, exhibiting no inhibitory activities against DNA topoisomerase II or ligase.


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Chemical Information

Catalog Num A13059
Actions Inhibitor
M. Wt 242.27
Formula C15H14O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 4707-32-8
Synonyms ARQ-501

Biological Activity

Beta-Lapachone is a selective DNA topoisomerase I inhibitor, exhibiting no inhibitory activities against DNA topoisomerase II or ligase.
Topo I IDO1
N/A0.44 μM


Solubility (25°C)* In vitro DMSO 33 mg/mL heating (136.21 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL (41.27 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.28 mL 206.38 mL 412.76mL
0.5 mM 8.26 mL 41.28 mL 82.55 mL
1 mM 4.13 mL 20.64 mL 41.28 mL
5 mM 0.83 mL 4.13 mL 8.26 mL

*The above data is based on the productmolecular weight 242.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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