Beta-Lapachone

Catalog No.: A13059

DNA topoisomerase II inhibitor

Beta-Lapachone

Beta-Lapachone Chemical Structure

CAS NO. 4707-32-8

Beta-Lapachone is a selective DNA topoisomerase I inhibitor, exhibiting no inhibitory activities against DNA topoisomerase II or ligase.

Availability: In stock

Package Price Qty
10 mg
$55.00
25 mg
$110.00
50 mg
$200.00
100 mg
$380.00
10mM * 1mL in DMSO
$75.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Xiaoling Li, .et al. Nanozyme-Augmented Tumor Catalytic Therapy by Self-Supplied H2O2 Generation, ACS Appl. Bio Mater, 2020, 3, 3, 1769-1778

Biological Activity

Beta-Lapachone is a selective DNA topoisomerase I inhibitor, exhibiting no inhibitory activities against DNA topoisomerase II or ligase.
Targets
Topo I IDO1
N/A0.44 μM
In vitro DMSO Warmed: 29 mg/mL (119.7 mM)
Water Insoluble
Ethanol 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.28 mL 206.38 mL 412.76 mL
0.5 mM 8.26 mL 41.28 mL 82.55 mL
1 mM 4.13 mL 20.64 mL 41.28 mL
5 mM 0.83 mL 4.13 mL 8.26 mL

*The above data is based on the productmolecular weight 242.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13059
Actions Inhibitor
CAS No. 4707-32-8
Formula C15H14O3
M. Wt 242.27
Purity >98%
Synonyms ARQ-501
SMILES CC1(CCC2=C(O1)C3=CC=CC=C3C(=O)C2=O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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