BI1002494 is a selective inhibitor of spleen tyrosine kinase (SYK) with oral bioavailability. It demonstrates potent inhibitory activity with an IC50 of 115 nM against high-affinity IgE receptor-mediated degranulation in mast cells and basophils. This compound is a valuable tool for studying immune responses and can be applied in a variety of immunology research applications.
BI1002494 is a selective inhibitor of spleen tyrosine kinase (SYK) with oral bioavailability. It demonstrates potent inhibitory activity with an IC50 of 115 nM against high-affinity IgE receptor-mediated degranulation in mast cells and basophils. This compound is a valuable tool for studying immune responses and can be applied in a variety of immunology research applications.
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