BIIB021

Catalog No.: A10143
HSP90 inhibitor
BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival.
Grouped product items
Product Name Price Stock Qty
BIIB021 5mg
$55.00
In stock
BIIB021 10mg
$80.00
In stock
BIIB021 50mg
$210.00
In stock
BIIB021 100mg
$320.00
In stock
BIIB021 10mM * 1mL in DMSO
$60.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's BIIB021 has been cited by 6 publications
  • Aydemir Asdemir, .et al. , Naunyn Schmiedebergs Arch Pharmacol ., 2024, Jan 19 PMID: 38240781
  • Celia Rouges, .et al. , Microorganisms, 2023, Nov 22;11(12):2837 PMID: 38137982
  • C M Güven, .et al. , Eur Rev Med Pharmacol Sci, 2023, Aug;27(15):7299-7308 PMID: 37606138
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • Ting-Yu Chang, .et al. , Biomed Pharmacother, 2021, Jun;138:111485 PMID: 33740521
  • Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113
Biological Activity
Discription BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival.
Targets
Target Value
Product Information
Catalog Num A10143
Formula C14H15ClN6O
Molecular Weight 318.8
CAS Number 848695-25-0
SMILES CC1=CN=C(C(=C1OC)C)CN2C=NC3=C2N=C(N=C3Cl)N
Synonyms CNF2024
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 60 mg/mL (188.22 mM)
Water Insoluble
Ethanol 2 mg/mL (6.27 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.37 mL 156.84 mL 313.68 mL
0.5 mM 6.27 mL 31.37 mL 62.74 mL
1 mM 3.14 mL 15.68 mL 31.37 mL
5 mM 0.63 mL 3.14 mL 6.27 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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