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| Description | BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival. | |||||
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| Targets |
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| Cell Research |
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| Catalog Num | A10143 |
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| Formula | C14H15ClN6O |
| Molecular Weight | 318.8 |
| CAS Number | 848695-25-0 |
| SMILES | CC1=CN=C(C(=C1OC)C)CN2C=NC3=C2N=C(N=C3Cl)N |
| Synonyms | CNF2024 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 60 mg/mL (188.22 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (6.27 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.37 mL | 156.84 mL | 313.68 mL |
| 0.5 mM | 6.27 mL | 31.37 mL | 62.74 mL |
| 1 mM | 3.14 mL | 15.68 mL | 31.37 mL |
| 5 mM | 0.63 mL | 3.14 mL | 6.27 mL |
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
