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- Hiroki Murano, .et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107-113
|Storage||at -20°C 3 years Powder|
|BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival.|
|Solubility (25°C) *||In vitro||DMSO||64 mg/mL (200.77 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||2 mg/mL (6.27 mM)|
|In vivo||30% propylene glycol, 5% Tween 80, 65% D5W||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||31.37 mL||156.84 mL||313.68mL|
|0.5 mM||6.27 mL||31.37 mL||62.74 mL|
|1 mM||3.14 mL||15.68 mL||31.37 mL|
|5 mM||0.63 mL||3.14 mL||6.27 mL|
*The above data is based on the productmolecular weight 318.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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