Biopterin

Catalog No.: A13901

NOS cofactor

Biopterin Chemical Structure

CAS NO. 22150-76-1

Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 uM after 48 hrs).

Availability: In stock

Package Price Qty
25 mg
$120.00
50 mg
$200.00
100 mg
$320.00

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Biological Activity

Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 uM after 48 hrs).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 42.16 mL 210.79 mL 421.59 mL
0.5 mM 8.43 mL 42.16 mL 84.32 mL
1 mM 4.22 mL 21.08 mL 42.16 mL
5 mM 0.84 mL 4.22 mL 8.43 mL

*The above data is based on the productmolecular weight 237.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13901
M. Wt 237.2
Formula C9H11N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 22150-76-1
Synonyms L-erythro-Biopterin, L-Biopterin, NSC 339699
SMILES CC(C(C1=CN=C2C(=N1)C(=O)N=C(N2)N)O)O

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